TY - JOUR AU - NECHITA, Ancuța AU - FILIMON, Razvan V. AU - FILIMON, Roxana M. AU - COLIBABA, Lucia-Cintia AU - GHERGHEL, Daniela AU - DAMIAN, Doina AU - PAȘA, Rodica AU - COTEA, Valeriu V. PY - 2018/12/21 Y2 - 2024/03/29 TI - In vitro Antifungal Activity of a New Bioproduct Obtained from Grape Seed Proanthocyanidins on Botrytis cinerea Mycelium and Spores JF - Notulae Botanicae Horti Agrobotanici Cluj-Napoca JA - Not Bot Horti Agrobo VL - 47 IS - 2 SE - Research Articles DO - 10.15835/nbha47111367 UR - https://www.notulaebotanicae.ro/index.php/nbha/article/view/11367 SP - 418-425 AB - <p style="text-align: justify;"><em>Botrytis cinerea </em>is a necrotrophic fungus that affects over 200 plant species. In vineyards, this pathogen is responsible for one of the most important diseases, commonly known as botrytis bunch rot or grey mould. Keeping infection under control with synthetic fungicides leads to an increased biological resistance of pathogen populations. An alternative way to synthetic products is to obtain natural fungicides by using bioactive compounds of plants. This study focuses on the antifungal properties of a new bioproduct obtained from polymeric proanthocyanidins extracted from grape seeds of ‘Fetească neagră’ variety. The bioproduct in solid state presented a total content of polyphenols of 0.625 mg GAE mg<sup>-1</sup>, a polyphenolic index of 17.40 and an antioxidant activity of 91.27% scavenged DPPH. The bioproduct with polyphenolic structure showed a moderate effect on the radial growth of fungal mycelium, at EC<sub>50</sub> values between 11.23 and 12.15 mg mL<sup>-1</sup>. Effective antifungal activity was showed in the inhibition of spore germination, where the EC<sub>50</sub> values varied from 1.14 to 1.47 mg mL<sup>-1</sup>. These <em>in vitro</em> results sustain the possibility of including the bioproduct in the category of natural fungicides for biological control against <em>Botrytis cinerea </em>fungus<em>.</em></p> ER -