Potential role of L-glutamic acid in mitigating cadmium toxicity in lentil (Lens culinaris Medik.) through modulating the antioxidant defence system and nutrient homeostasis


  • Jannatul FARDUS Kagawa University, Faculty of Agriculture, Laboratory of Plant Stress Responses, Ikenobe 2393, Miki-cho, Kita gun, Kagawa, 761-0795 (JP)
  • Md. Shahadat HOSSAIN Kagawa University, Faculty of Agriculture, Laboratory of Plant Stress Responses, Ikenobe 2393, Miki-cho, Kita gun, Kagawa, 761-0795 (JP)
  • Masayuki FUJITA Kagawa University, Faculty of Agriculture, Laboratory of Plant Stress Responses, Ikenobe 2393, Miki-cho, Kita gun, Kagawa, 761-0795 (JP)




amino acid, cadmium stress, cadmium uptake, enzyme activities, oxidative damage, ROS


DOI: 10.15835/nbha49412485 

Using phosphate fertilizers and wastewater as a source of irrigation and residuals from industries have considerably increased the level of cadmium (Cd) in soil which severely reduced the growth and yield of crop. L-glutamic acid (L-Glu), an amino acid, plays key roles in plant stress tolerance. Hence, the current study was conducted to determine the potential role of L-Glu pre-treatment in alleviating Cd-induced toxicity in lentil (Lens culinaris Medik.). Lentil seedlings were exposed to two doses of Cd (1 and 2 mM CdCl2) with or without 10 mM L-Glu pre-treatment. The results suggested that a high dose of Cd negatively affected the shoot dry weight, root dry weight, and photosynthetic pigments (chlorophylls and carotenoids). Furthermore, Cd stress induced severe oxidative damage, a reduction in catalase (CAT) activity and ascorbate (AsA) content, and accumulation of Cd in both the roots and shoots. Adding L-Glu protected the photosynthetic pigments of the lentil seedlings and thus improved the growth of the seedlings. In addition, L-Glu pre-treatment enhanced the ascorbate (AsA) content; increased the activity of enzymes such as catalase, ascorbate peroxidase, monodehydroascorbate reductase, and glutathione peroxidase. L-Glu was also reduced Cd uptake and translocation, which in turn alleviated the oxidative damage in the Cd-stressed seedlings indicated the potential role of this chemical. Results suggest that pre-treatment with L-Glu reduces Cd toxicity in lentil seedlings by inhibiting Cd accumulation and by reducing oxidative damage.


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Abogadallah GM (2010). Insights into the significance of antioxidative defense under salt stress. Plant Signaling and Behavior 5:369-374. https://doi.org/10.4161/psb.5.4.10873

Ahmad P, Abdel Latef AA, Abd Allah EF, Hashem A, Sarwat M, Anjum NA, Gucel S (2016). Calcium and potassium supplementation enhanced growth, osmolyte secondary metabolite production, and enzymatic antioxidant machinery in cadmium-exposed chickpea (Cicer arietinum L.). Frontiers and Plant Science 7:513. https://doi.org/10.3389/fpls.2016.00513

Andrews M, Andrews ME (2017). Specificity in legume-rhizobia symbioses. International Journal of Molecular Sciences 18:705. https://doi.org/10.3390/ijms18040705

Anjum SA, Tanveer M, Hussain S, Shahzad B, Ashraf U, Fahad S, … Bajwa AA (2016). Osmoregulation and antioxidant production in maize under combined cadmium and arsenic stress. Environmental Science and Pollution Research 23:11864-11875. https://doi.org/10.1007/s11356-016-6382-1

Asgher M, Khan NA, Khan MIR, Fatma M, Masood A (2014). Ethylene production is associated with alleviation of cadmium-induced oxidative stress by sulfur in mustard types differing in ethylene sensitivity. Ecotoxicology and Environmental Safety 106:54-61. https://doi.org/10.1016/j.ecoenv.2014.04.017

Bansal R, Priya S, Dikshit HK, Jacob SR, Rao M, Bana RS, … Siddique K (2021). Growth and antioxidant responses in iron-biofortified lentil under cadmium stress. Toxics 9:182. https://doi.org/10.3390/toxics9080182

Bashri G, Prasad SM (2016). Exogenous IAA differentially affects growth, oxidative stress and antioxidants system in Cd stressed Trigonella foenum-graecum L. seedlings: Toxicity alleviation by up-regulation of ascorbate-glutathione cycle. Ecotoxicology and Environmental Safety 132:329-338. https://doi.org/10.1016/j.ecoenv.2016.06.015

Bates LS, Waldren RP, Teare ID (1973). Rapid determination of free proline for water-stress studies. Plant and Soil 39:205-207. https://doi.org/10.1007/BF00018060

Bayçu G, Moustaka J, Gevrek N, Moustakas M (2018). Chlorophyll fluorescence imaging analysis for elucidating the mechanism of photosystem II acclimation to cadmium exposure in the hyperaccumulating plant Noccaea caerulescens. Materials 11:2580. https://doi.org/10.3390/ma11122580

Bočová B, Huttová J, Mistrík I, Tamás L (2013). Auxin signalling is involved in cadmium-induced glutathione-S-transferase activity in barley root. Acta Physiologiae Plantarum 35:2685-2690. https://doi.org/10.1007/s11738-013-1300-3

Bradford MM (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72:248-254. https://doi.org/10.1016/0003-2697(76)90527-3

Chen D, Chen D, Xue R, Long J, Lin X, Lin Y, … Song Y (2019). Effects of boron, silicon and their interactions on cadmium accumulation and toxicity in rice plants. Journal of Hazardous Materials 367:447-455. https://doi.org/10.1016/j.jhazmat.2018.12.111

Corpas FJ, Palma JM (2020). H2S signaling in plants and applications in agriculture. Journal of Advanced Research 24:131-137. https://doi.org/10.1016/j.jare.2020.03.011

Cuypers A, Plusquin M, Remans T, Jozefczak M, Keunen E, Gielen H, … Nawrot T (2010). Cadmium stress: An oxidative challenge. BioMetals 23:927-940. https://doi.org/10.1007/s10534-010-9329-x

Dionisio-Sese ML, Tobita S (1998). Antioxidant responses of rice seedlings to salinity stress. Plant Science 135:1-9. https://doi.org/10.1016/S0168-9452(98)00025-9

Fardus J, Hossain M, Fujita M (2021). Modulation of the antioxidant defense system by exogenous L-glutamic acid application enhances salt tolerance in lentil (Lens culinaris Medik.). Biomolecules 11:587. https://doi.org/10.3390/biom11040587

Feizi H, Agheli N, Sahabi H (2020). Titanium dioxide nanoparticles alleviate cadmium toxicity in lentil (Lens culinaris Medic) seeds. Acta Agriculturae Slovenica 116:59-68. http://dx.doi.org/10.14720/aas.2020.116.1.1116

Forde BG, Lea PJ (2007). Glutamate in plants: metabolism, regulation, and signalling. Journal of Experimental Botany 58:2339-2358. https://doi.org/10.1093/jxb/erm121

Forde BG (2014). Glutamate signalling in roots. Journal of Experimental Botany 65:779-787. https://doi.org/10.1093/jxb/ert335

Foti C, Khah EM, Pavli OI (2019). Germination profiling of lentil genotypes subjected to salinity stress. Plant Biology 21:480-486. https://doi.org/10.1111/plb.12714

Foyer CH, Noctor G (2005). Redox homeostasis and antioxidant signaling: A metabolic interface between stress perception and physiological responses. The Plant Cell 17:1866-1875. https://doi.org/10.1105/tpc.105.033589

Gill SS, Tuteja N (2010). Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants. Plant Physiology and Biochemistry 48:909-930. https://doi.org/10.1016/j.plaphy.2010.08.016

Gratão PL, Monteiro CC, Tezotto T, Carvalho RF, Alves LR, Peters LP, Azevedo RA (2015). Cadmium stress antioxidant responses and root-to-shoot communication in grafted tomato plants. BioMetals 28:803-816. https://doi.org/10.1007/s10534-015-9867-3

Halliwell B (2006). Reactive species and antioxidants. Redox biology is a fundamental theme of aerobic life. Plant Physiology 141:312-322. https://doi.org/10.1104/pp.106.077073

He F, Arce AL, Schmitz G, Koornneef M, Novikova P, Beyer A, De Meaux J (2016). The footprint of polygenic adaptation on stress-responsive cis-regulatory divergence in the Arabidopsis genus. Molecular Biology and Evolution 33:2088-2101. https://doi.org/10.1093/molbev/msw096

Heath RL, Packer L (1968). Photoperoxidation in isolated chloroplasts: I. Kinetics and stoichiometry of fatty acid peroxidation. Archives of Biochemistry and Biophysics 125:189-198. https://doi.org/10.1016/0003-9861(68)90654-1

Horemans N, Van Hees M, Van Hoeck A, Saenen E, De Meutter T, Nauts R, … Vandenhove H (2015). Uranium and cadmium provoke different oxidative stress responses in Lemna minor L. Plant Biology 17:91-100. https://doi.org/10.1111/plb.12222

Hussain A, Ali S, Rizwan M, Zia-ur-Rehman MZ, Javed MR, Imran M, … Nazir R (2018). Zinc oxide nanoparticles alter the wheat physiological response and reduce the cadmium uptake by plants. Environmental Pollution 242:1518-1526. https://doi.org/10.1016/j.envpol.2018.08.036

Huybrechts M, Cuypers A, Deckers J, Iven V, Vandionant S, Jozefczak M, Hendrix S (2019). Cadmium and plant development: An agony from seed to seed. International Journal of Molecular Sciences 20:3971. https://doi.org/10.3390/ijms20163971

Ismael MA, Elyamine AM, Moussa MG, Cai M, Zhao X, Hu C (2019). Cadmium in plants: Uptake, toxicity, and its interactions with selenium fertilizers. Metallomics 11:255-277. https://doi.org/10.1039/c8mt00247a

Wu J-W, Shi Y, Zhu Y-X, Wang Y-C, Gong H-J (2013). Mechanisms of enhanced heavy metal tolerance in plants by silicon: A review. Pedosphere 23:815-825. https://doi.org/10.1016/S1002-0160(13)60073-9

Kan CC, Chung TY, Wu HY, Juo YA, Hsieh MH (2017). Exogenous glutamate rapidly induces the expression of genes involved in metabolism and defense responses in rice roots. BMC Genomics 18:186. https://doi.org/10.1186/s12864-017-3588-7

Kapoor D, Singh MP, Kaur S, Bhardwaj R, Zheng B, Sharma A (2019). Modulation of the functional components of growth, photosynthesis, and antioxidant stress markers in cadmium exposed Brassica juncea L. Plants 8:260. https://doi.org/10.3390/plants8080260

Kaur G, Asthir BJBP (2015). Proline: A key player in plant abiotic stress tolerance. Biologia Plantarum 59:609-619. https://doi.org/10.1007/s10535-015-0549-3

Kaya C, Ashraf M, Alyemeni MN, Ahmad P (2019). Responses of nitric oxide and hydrogen sulfide in regulating oxidative defence system in wheat plants grown under cadmium stress. Physiologia Plantarum 168:345-360. https://doi.org/10.1111/ppl.13012

Kaya C, Ashraf M, Alyemeni MN, Ahmad P (2020). The role of nitrate reductase in brassinosteroid-induced endogenous nitric oxide generation to improve cadmium stress tolerance of pepper plants by upregulating the ascorbate-glutathione cycle. Ecotoxicology and Environmental Safety 196:110483. https://doi.org/10.1016/j.ecoenv.2020.110483

Keramat B, Kalantari KM, Arvin MJ (2010). Effects of methyl jasmonate treatment on alleviation of cadmium damages in soybean. Journal of Plant Nutrition 33:1016-1025. https://doi.org/10.1080/01904161003728685

Khademian R, Asghari B, Sedaghati B, Yaghoubian Y (2019). Plant beneficial rhizospheric microorganisms (PBRMs) mitigate deleterious effects of salinity in sesame (Sesamum indicum L.): Physio-biochemical properties, fatty acids composition and secondary metabolites content. Industrial Crops and Products 136:129-139. https://doi.org/10.1016/j.indcrop.2019.05.002

Khan MA, Khan S, Khan A, Alam M (2017). Soil contamination with cadmium, consequences and remediation using organic amendments. Science of The Total Environment 601:1591-1605. https://doi.org/10.1016/j.scitotenv.2017.06.030

Khan MN, Al Solami MA, Basahi RA, Siddiqui MH, Al-Huqail AA, Abbas ZK, … Khan F (2020). Nitric oxide is involved in nano-titanium dioxide-induced activation of antioxidant defense system and accumulation of osmolytes under water-deficit stress in Vicia faba L. Ecotoxicology and Environmental Safety 190:110152. https://doi.org/10.1016/j.ecoenv.2019.110152

Khodarahmi S, Khoshgoftarmanesh AH (2017). The effect of cadmium toxicity and silicon supplementation on the activity of antioxidative enzymes and the concentration of zinc and iron in hydroponically grown cucumber. Communications in Soil Science and Plant Analysis 48:51-62. https://doi.org/10.1080/00103624.2016.1253720

Kong D, Ju C, Parihar A, Kim S, Cho D, Kwak JM (2015). Arabidopsis glutamate receptor homolog3.5 modulates cytosolic Ca2+ level to counteract effect of abscisic acid in seed germination. Plant Physiology 167:1630-1642. https://doi.org/10.1104/pp.114.251298

Krantev A, Yordanova R, Janda T, Szalai G, Popova L (2008). Treatment with salicylic acid decreases the effect of cadmium on photosynthesis in maize plants. Journal of Plant Physiology 165:920-931. https://doi.org/10.1016/j.jplph.2006.11.014

Kurtyka R, Małkowski E, Kita A, Karcz W (2008). Effect of calcium and cadmium on growth and accumulation of cadmium, calcium, potassium and Sodium in Maize Seedlings. Polish Journal of Environmental Studies 17:51-56. https://www.researchgate.net/publication/259852721

Küpper H, Andresen E (2016). Mechanisms of metal toxicity in plants. Metallomics 8:269-285. https://doi.org/10.1039/c5mt00244c

La VH, Lee BR, Islam M, Mamun M, Park SH, Bae DW, Kim TH (2020). Characterization of glutamate-mediated hormonal regulatory pathway of the drought responses in relation to proline metabolism in Brassica napus L. Plants 9:512. https://doi.org/10.3390/plants9040512

Latef AA (2013). Growth and some physiological activities of pepper (Capsicum annuum L.) in response to cadmium stress and mycorrhizal symbiosis. Journal of Agricultural Science and Technology 15:1437-1448. http://jast.modares.ac.ir/article-23-11530-en.html

Li Q, Wang G, Wang Y, Yang D, Guan C, Ji J (2019). Foliar application of salicylic acid alleviates the cadmium toxicity by modulation the reactive oxygen species in potato. Ecotoxicology and Environmental Safety 172:317-325. https://doi.org/10.1016/j.ecoenv.2019.01.078

Liu Z, Ding Y, Wang F, Ye Y, Zhu C (2016). Role of salicylic acid in resistance to cadmium stress in plants. Plant Cell Reports 35:719-731. https://doi.org/10.1007/s00299-015-1925-3

Lu Y, Wang QF, Li J, Xiong J, Zhou LN, He SL, … Liu H (2019). Effects of exogenous sulfur on alleviating cadmium stress in tartary buckwheat. Scientific Reports 9:1-12. https://doi.org/10.1038/s41598-019-43901-4

Małecka A, Konkolewska A, Hanć A, Barałkiewicz D, Ciszewska L, Ratajczak E, … Jarmuszkiewicz W (2019). Insight into the phytoremediation capability of Brassica juncea (v. Malopolska): Metal accumulation and antioxidant enzyme activity. International Journal of Molecular Sciences 20:4355. https://doi.org/10.3390/ijms20184355

Mishra S, Bharagava RN, More N, Yadav A, Zainith S, Mani S, Chowdhary P (2019). Heavy metal contamination: an alarming threat to environment and human health. In Environmental biotechnology: For sustainable future; Springer: Singapore 103-125. https://doi.org/10.1007/978-981-10-7284-0_5

Muneer S, Kim TH, Choi BC, Lee BS, Lee JH (2014). Effect of CO, NOx and SO2 on ROS production, photosynthesis and ascorbate–glutathione pathway to induce Fragaria× annasa as a hyperaccumulator. Redox Biology 2:91-98. https://doi.org/10.1016/j.redox.2013.12.006

Nahar K, Hasanuzzaman M, Rahman A, Alam M, Mahmud JA, Suzuki T, Fujita M (2016). Polyamines confer salt tolerance in mung bean (Vigna radiata L.) by reducing sodium uptake, improving nutrient homeostasis, antioxidant defense, and methylglyoxal detoxification systems. Frontiers in Plant Science 7:1104. https://doi.org/10.3389/fpls.2016.01104

Nazar R, Iqbal N, Masood A, Khan MIR, Syeed S, Khan NA (2012). Cadmium toxicity in plants and role of mineral nutrients in its alleviation. American Journal of Plant Sciences 3:4. https://doi.org/10.4236/ajps.2012.310178

Nephali L, Piater LA, Dubery IA, Patterson V, Huyser J, Burgess K, Tugizimana F (2020). Biostimulants for plant growth and mitigation of abiotic stresses: A metabolomics perspective. Metabolites 10:505. https://doi.org/10.3390/metabo10120505

Noctor G, Mhamdi A, Foyer CH (2016). Oxidative stress and antioxidative systems: recipes for successful data collection and interpretation. Plant, Cell and Environment 39:1140-1160. https://doi.org/10.1111/pce.12726

Per TS, Masood A, Khan NA (2017). Nitric oxide improves S-assimilation and GSH production to prevent inhibitory effects of cadmium stress on photosynthesis in mustard (Brassica juncea L.). Nitric Oxide 68:111-124. https://doi.org/10.1016/j.niox.2016.12.012

Qadir S, Jamshieed S, Rasool S, Ashraf M, Akram NA, Ahmad P (2014). Modulation of plant growth and metabolism in cadmium-enriched environments. Reviews of Environmental Contamination and Toxicology 51-88. https://doi.org/10.1007/978-3-319-03777-6_4

Qiu XM, Sun YY, Ye XY, Li ZG (2020). Signaling role of glutamate in plants. Frontiers in Plant Science 10:1743. https://doi.org/10.3389/fpls.2019.01743

Rizwan M, Ali S, Adrees M, Ibrahim M, Tsang DC, Zia-ur-Rehman M, … Ok YS (2017). A critical review on effects, tolerance mechanisms and management of cadmium in vegetables. Chemosphere 182:90-105. https://doi.org/10.1016/j.chemosphere.2017.05.013

Rizwan M, Ali S, Zia-ur-Rehman MZ, Rinklebe J, Tsang DC, … Ok YS (2018). Cadmium phytoremediation potential of Brassica crop species: A review. Science of The Total Environment 631:1175-1191. https://doi.org/10.1016/j.scitotenv.2018.03.104

Rohani N, Daneshmand F, Vaziri A, Mahmoudi M, Saber-Mahani F (2019). Growth and some physiological characteristics of Pistacia vera L. cv Ahmad Aghaei in response to cadmium stress and Glomus mosseae symbiosis. South African Journal of Botany124:499-507. https://doi.org/10.1016/j.sajb.2019.06.001

Savvides A, Ali S, Tester M, Fotopoulos V (2016). Chemical priming of plants against multiple abiotic stresses: mission possible? Trends in Plant Science 21:329-340. https://doi.org/10.1016/j.tplants.2015.11.003

Sh Sadak M, Abdelhamid MT, Schmidhalter U (2015). Effect of foliar application of amino acids on plant yield and some physiological parameters in bean plants irrigated with seawater. Acta Biológica Colombiana 20:141-152. https://doi.org/10.15446/abc.v20n1.42865

Shah AA, Ahmed S, Yasin NA (2019). 24-epibrassinolide triggers cadmium stress mitigation in Cucumis sativus through intonation of antioxidant system. South African Journal of Botany 127:349-360. https://doi.org/10.1016/j.sajb.2019.11.003

Shahwar D, Ansari MYK, Choudhary S (2019). Induction of phenotypic diversity in mutagenized population of lentil (Lens culinaris Medik) by using heavy metal. Heliyon 5. https://doi.org/10.1016/j.heliyon.2019.e01722

Shanying HE, Xiaoe YANG, Zhenli HE, Baligar VC (2017). Morphological and physiological responses of plants to cadmium toxicity: A review. Pedosphere 27:421-438. https://doi.org/10.1016/S1002-0160(17)60339-4

Song X, Yue X, Chen W, Jiang H, Han Y, Li X (2019). Detection of cadmium risk to the photosynthetic performance of Hybrid Pennisetum. Frontiers in Plant Science 10:798. https://doi.org/10.3389/fpls.2019.00798

Sun H, Wang X, Shang L, Zhou Z, Wang R (2017). Cadmium accumulation and its effects on nutrient uptake and photosynthetic performance in cucumber (Cucumis sativus L.). Philippine Agricultural Scientist 100:263-270. https://www.researchgate.net/publication/320735530

Suzuki N, Koussevitzky SHAI, Mittler RON, Miller GAD (2012). ROS and redox signaling in the response of plants to abiotic stress. Plant, Cell and Environment 35:259-270. https://doi.org/10.1111/j.1365-3040.2011.02336.x

Toyota M, Spencer D, Sawai-Toyota S, Jiaqi W, Zhang T, Koo AJ, Howe GA, Gilroy S (2018). Glutamate triggers long-distance, calcium-based plant defense signaling. Science 361:1112-1115. https://doi.org/10.1126/science.aat7744

Tran TA, Popova LP (2013). Functions and toxicity of cadmium in plants: Recent advances and future prospects. Turkish Journal of Botany 37:1-13. https://doi.org/10.3906/bot-1112-16

Wang J, Anderson CW, Xing Y, Fan Y, Xia J, Shaheen SM, … Feng X (2018). Thiosulphate-induced phytoextraction of mercury in Brassica juncea: Spectroscopic investigations to define a mechanism for Hg uptake. Environmental Pollution 242:986-993. https://doi.org/10.1016/j.envpol.2018.07.065

Wellburn AR (1994). The spectral determination of chlorophylls a and b, as well as total carotenoids, using various solvents with spectrophotometers of different resolution. Journal of Plant Physiology 144:307-313. https://doi.org/10.1016/S0176-1617(11)81192-2

Wu J, Mock HP, Giehl RF, Pitann B, Mühling KH (2019). Silicon decreases cadmium concentrations by modulating root endodermal suberin development in wheat plants. Journal of Hazardous Materials 364:581-590. https://doi.org/10.1016/j.jhazmat.2018.10.052

Wu S, Wang Y, Zhang J, Gong X, Zhang Z, Sun J, Chen X, Wang Y (2021). Exogenous melatonin improves physiological characteristics and promotes growth of strawberry seedlings under cadmium stress. Horticultural Plant Journal 7:13-22. https://doi.org/10.1016/j.hpj.2020.06.002

Xia H, Zhao X, Ni Z, Liang D (2018). Enzyme’s activities analysis involved in AsA-GSH cycle of yellow-flesh kiwifruit genotypes. In IOP Conference Series: Materials Science and Engineering 392:052019. IOP Publishing. https://doi.org/10.1088/1757-899X/392/5/052019

Xin J, Zhao XH, Tan QL, Sun XC, Zhao YY, Hu CX (2019). Effects of cadmium exposure on the growth, photosynthesis, and antioxidant defense system in two radish (Raphanus sativus L.) cultivars. Photosynthetica 57:967-973. https://doi.org/10.32615/ps.2019.076

Xu LL, Fan ZY, Dong YJ, Kong J, Bai XY (2015). Effects of exogenous salicylic acid and nitric oxide on physiological characteristics of two peanut cultivars under cadmium stress. Biologia Plantarum 59:171-182. https://doi.org/10.1007/s10535-014-0475-9

Yang J, Sun H, Qin J, Wang X, Chen W (2021). Impacts of Cd on temporal dynamics of nutrient distribution pattern of Bletilla striata, a traditional Chinese medicine plant. Agriculture 11:594. https://doi.org/10.3390/agriculture11070594

Yang SH, Wang LJ, Li SH (2007). Ultraviolet-B irradiation-induced freezing tolerance in relation to antioxidant system in winter wheat (Triticum aestivum L.) leaves. Environmental and Experimental Botany 60:300-307. https://doi.org/10.1016/j.envexpbot.2006.12.003

Yotsova EK, Dobrikova AG, Stefanov MA, Kouzmanova M, Apostolova EL (2018). Improvement of the rice photosynthetic apparatus defence under cadmium stress modulated by salicylic acid supply to roots. Theoretical and Experimental Plant Physiology 30:57-70. https://doi.org/10.1007/s40626-018-0102-9

Zheng Y, Luo L, Wei J, Chen Q, Yang Y, Hu X, Kong X (2018). The glutamate receptors AtGLR1. 2 and AtGLR1. 3 increase cold tolerance by regulating jasmonate signaling in Arabidopsis thaliana. Biochemical and Biophysical Research Communications 506:895-900. https://doi.org/10.1016/j.bbrc.2018.10.153

Zhou J, Hao M, Liu Y, Huang G, Fu Q, Zhu J, Hu H (2018). Effects of exogenous sulfur on growth and Cd uptake in Chinese cabbage (Brassica campestris spp. pekinensis) in Cd-contaminated soil. Environmental Science and Pollution Research 25:15823-15829. https://doi.org/10.1007/s11356-018-1712-0


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FARDUS, J., HOSSAIN, M. S., & FUJITA, M. (2021). Potential role of L-glutamic acid in mitigating cadmium toxicity in lentil (Lens culinaris Medik.) through modulating the antioxidant defence system and nutrient homeostasis. Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 49(4), 12485. https://doi.org/10.15835/nbha49412485



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DOI: 10.15835/nbha49412485