Composition of Lavandula angustifolia L. cultivated in Transylvania, Romania

Authors

  • Camelia OROIAN University of Agricultural Sciences and Veterinary Medicine, Faculty of Horticulture, 3-5 Calea Mănăștur, Cluj-Napoca 400372 (RO)
  • Antonia ODAGIU University of Agricultural Sciences and Veterinary Medicine, Faculty of Agriculture, 3-5 Calea Mănăștur, Cluj-Napoca 400372 (RO)
  • Csaba Pal RACZ University Babes-Bolyai, Faculty of Chemistry and Chimical Inginery, 11 Arany Janos St., Cluj-Napoca 400028 (RO)
  • Ioan OROIAN University of Agricultural Sciences and Veterinary Medicine, Faculty of Agriculture, 3-5 Calea Mănăștur, Cluj-Napoca 400372 (RO)
  • Iulia C. MUREȘAN University of Agricultural Sciences and Veterinary Medicine, Faculty of Horticulture, 3-5 Calea Mănăștur, Cluj-Napoca 400372 (RO)
  • Marcel DUDA University of Agricultural Sciences and Veterinary Medicine, Faculty of Agriculture, 3-5 Calea Mănăștur, Cluj-Napoca 400372 (RO)
  • Marioara ILEA University of Agricultural Sciences and Veterinary Medicine, Faculty of Horticulture, 3-5 Calea Mănăștur, Cluj-Napoca 400372 (RO)
  • Ioan BRAȘOVEAN University of Agricultural Sciences and Veterinary Medicine, Faculty of Agriculture, 3-5 Calea Mănăștur, Cluj-Napoca 400372 (RO)
  • Cristian IEDERAN University of Agricultural Sciences and Veterinary Medicine, Faculty of Agriculture, 3-5 Calea Mănăștur, Cluj-Napoca 400372 (RO)
  • Zamfir MARCHIȘ University of Agricultural Sciences and Veterinary Medicine, Faculty of Animal Husbandry and Biotechnology, 3-5 Calea Mănăștur, Cluj-Napoca 400372 (RO)

DOI:

https://doi.org/10.15835/nbha47311565

Keywords:

chemotype; cluster; distribution; essential oil; lavender; terpene

Abstract

An increasing market demand concerning lavender essential oil is reported. Identification and characterization of the main compounds of this oil is needed, in order to identify chemotypes. This information is useful for further uses of the produced oil. Essential oil extracted from two Lavandula angustifolia L. varieties, cultivated in different areas of Transylvania, Romania, was analysed from the point of view of qualitative and quantitative composition, using gas-chromatography. Basic statistics was used for calculation of essential oil compounds means and dispersion parameters, while the profile of the essential oil composition was emphasized using Box-Plot diagrams and cluster analysis. Nine compounds, in different amounts were quantified, and two chemotypes, corresponding to ‘Mailette’ and ‘Vera’ varieties were established (linalool, and linalyl acetate, respectively). Differences in essential oil composition are recorded in ‘Vera’ variety corresponding to ‘Vera’ linalyl acetate chemotype, function of specific condition of lavender cultivation area.

References

Al-Wassouf G (2018). Chemical composition of the essential oil of Lavandula angustifolia from Syria. Chemistry and Materials Research 10(1):1-6.

Beale DJ, Morrison PD, Karpe AV, Dunn MS (2017). Chemometric analysis of lavender essential oils using targeted and untargeted GC-MS acquired data for the RAPID identification and characterization of oil quality. Molecules 22(8):1339.

Burdon RCF, Junker RR, Scofield DG, Parachnowitsch AL (2018). Bacteria colonising Penstemon digitalis show volatile and tissue-specific responses to a natural concentration range of the floral volatile linalool. Chemoecology 28(1):11-19.

Caldas GFR, da Silva Oliveira AR, Araújo AV, Lafayette SSL, Albuquerque GS, J da Costa Silva N, … Wanderley AG (2015). Gastroprotective mechanisms of the monoterpene 1, 8-cineole (Eucalyptol). PLoS One 10(8): e0134558.

Camargo SB, Simões LO, Medeiros CFA, de Melo Jesus A, Fregoneze JB, Evangelista A, … Silva DF (2018). Antihypertensive potential of linalool and linalool complexed with β-cyclodextrin: Effects of subchronic treatment on blood pressure and vascular reactivity. Biochemical Pharmacology 51:38-46.

Caputo L, Reguilon MD, José Mińarro, De Feo V, Rodriguez-Arias M (2018). Lavandula angustifolia essential oil and linalool counteract social aversion induced by social defeat. Molecules 23(10):2694.

Cardia GFE, Silva-Filho SE, Silva EL, Uchida NS, Cavalcante HAO, Cassarotti LL, … Cuman RKN (2018). Effect of lavender (Lavandula angustifolia) essential oil on acute inflammatory response. Evidence-Based Complementary and Alternative Medicine1413940.

Cavanagh HMA, Wilkinson JM (2002). Biological activities of lavender essential oil. Phytotherapy Research 16(4):301-308.

Chioca LR, Ferro MM, Baretta P, Oliveira SM, Silva CR, Ferreira J, Losso EM, Andreatini R (2013). Anxiolytic-like effect of lavender essential oil inhalation in mice: Participation of serotonergic but not GABAA/benzodiazepine neurotransmission. Journal of Ethnopharmacology 147(2):412-418.

Cîmpean A (2000). Fermented milk product: an excellent probiotic for organic production of pig meat. Agricultura Revistă de Știință și Practică Agricolă 9(1-4):80-81.

Cîmpean A, Morar R, Paşca I, Pusta D, Mierliţă D, Borzaşi M (2000). Effect of lactic flora from fermented dairy products, a scientific basis for the study of microbial probiotics in pigs. Bulletin UASVM 54:201-204.

Cîmpean A, Morar R, Paşca I, Pusta D, Mierliţă D, Borzaşi M (2000). Effect of lactic flora from fermented dairy products, a scientific basis for the study of microbials in pigs. Lucrări Știinţifice 43(2):406-411.

Cowen PJ, Browning M (2015). What has serotonin to do with depression? World Psychiatry 14(2):158-160.

Eide HA, Halvorsen AR, Sandhu V, Fane A, Berg J, Haakensen VD (2016) Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease. Clinical and Translational Immunology 5(11):e109.

Gassan al-Wassouf (2018). Chemical composition of the essential oil of Lavandula angustifolia from Syria. Chemistry and Materials Research 10(1)-1-6.

Hajhashemi V, Ghannadi A, Sharif B (2003). Anti-infammatory and analgesic properties of the leaf extracts and essential oil of Lavandula angustifolia Mill. Journal of Ethnopharmacology 89(1):67-71.

Hamidpour R, Hamidpour S, Hamidpour M, Shahlari M (2012). Camphor (Cinnamomum camphora), a traditional remedy with the history of treating several diseases. International Journal of Case Reports and Images 4(2):86-89.

Ilić AS, Antić MP, Jelačić SC, Šolević Knudsen TM (2019). Chemical composition of the essential oils of three Ocimum basilicum L. cultivars from Serbia. Notulae Botanicae Horti Agrobotanici Cluj-Napoca 47(2):347-351.

Inouye S, Takizawa T, Yamaguchi H (2001). Antibacterial activity of essential oils and their major constituents against respiratory tract pathogens by gaseous contact. Journal of Antimicrobial Activity 47(5):565-573.

Kara N, Baydar H (2012). Essential oil contents and composition of lavenders and lavandins cultivated in Turkey. Research on Crops 13(2):675-681.

Kasper S, Gastpar M, Müller WE, Olz, HP, Möller HJ, Dienel A, Schläfke S (2010). Silexan, an orally administered Lavandula oil preparation, is effective in the treatment of “subsyndromal” anxiety disorder: a randomized, double-blind, placebo controlled trial. International Clinical Psychopharmacology 25(5):277-287.

Kim JR, Kang P, Lee HS, Kim KY, Seol GH (2017). Cardiovascular effects of linalyl acetate in acute nicotine exposure. Environmental Health and Preventive Medicine 22(1):42.

Kim KY, Hyo Jin Seo, Sun Seek Min, Park M, Hee Seol G (2014). The effect of 1,8-cineole inhalation on preoperative anxiety: A randomized clinical trial. Evidence-Based Complementary and Alternative Medicine 820126.

Kwon S, Hsieh YS, Shin YK, Kang P, Seol GH (2018). Linalyl acetate prevents olmesartan-induced intestinal hypermotility mediated by interference of the sympathetic inhibitory pathway in hypertensive rat. Biomedicine and Pharmacotherapy 102:362-368.

Lafhal S, Vanloot P, Bombarda I, Kister J, Dupuy N (2016). Chemometric analysis of French lavender and lavandin essential oils by near infrared spectroscopy. Industrial Crops and Products 80:156-164.

Lau AA, Crawley AC, Hopwood JJ, Hemsley KM (2008). Open field locomotor activity and anxiety-related behaviors in mucopolysaccharidosis type IIIA mice. Behavioural Brain Research 191(1):130-136.

Leite AM, Lima EDO, Souza ELD, Diniz MDFFM, Trajano VN, Medeiros IAD (2007). Inhibitory effect of beta-pinene, alpha-pinene and eugenol on the growth of potential infectious endocarditis causing Gram-positive bacteria. Revista Brasileira de Ciências Farmacêuticas 43(1):121-126.

Lesage-Meessen L, Bou M, Sigoillot JC, Faulds CB, Lomascolo A (2015). Essential oils and distilled straws of lavender and lavandin: a review of current use and potential application in white biotechnology. Applied Microbiology and Biotechnology 99(8):3375-3385.

Linck VDM, da Silva AL, Figueiró M, Caramao EB, Moreno PRH, Elisabetsky E (2010). Effects of inhaled Linalool in anxiety, social interaction and aggressive behavior in mice. Phytomedicine 17(8-9):679-683.

Lionetto MG, Caricato R, Calisi A, Giordano ME, Schettino T (2013). Acetylcholinesterase as a biomarker in environmental and occupational medicine: New insights and future perspectives. BioMed Research International 321213.

Moss M, Oliver I (2012). Plasma 1,8-cineole correlates with cognitive performance following exposure to rosemary essential oil aroma. Therapeutic Advances in Psychopharmacology 2(3):103-113.

Nardoni S, Ebani VV, D’Ascenzi C, Pistelli L, Mancianti F (2018). Sensitivity of entomopathogenic fungi and bacteria to plants secondary metabolites, for an alternative control of Rhipicephalus (Boophilus) microplus in cattle. Frontiers in Pharmacology 9:937.

Nuzzo RL (2016). The box plots alternative for visualizing quantitative data. PM&R 8(3):268-272.

Ognyanov I (1984). Bulgarian lavender and Bulgarian lavender oil. Perfumer and Flavorist 8(6):29-41.

Peana AT, D'Aquila PS, Panin F, Serra G, Pippia P, Maretti MDL (2002). Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils. Phytomedicine 9(8):721-726.

Pereira I, Severino P, Santo AC, Silva AM, Souto EB (2018). Linalool bioactive properties and potential applicability in drug delivery systems. Colloids and Surfaces B: Biointerfaces 171:566-578.

Petruț G, Muste S, Mureșan C, Mureșan AE, Vlaic R, Chiș S, … Pop A (2017). Flavour compounds of Lavandula angustifolia L. to use in food preservation. Hop and Medicinal Plants Year XXV(1-2):38-46.

Poutaraud A, Guilloteau L, Gros C, Lobstein A, Meziani S, Steyer D, … Lansade L (2018). Lavender essential oil decreases stress response of horses. Environmental Chemistry Letters 16(2):539-544.

Prashar A, Locke IC, Evans CS (2004). Cytotoxicity of lavender oil and its major components to human skin cells. Cell Proliferation 37(3):221-229.

Prusinowska R, Krzysztof B, Smigielski B (2014). Composition, biological properties and therapeutic effects of lavender (Lavandula angustifolia L.). A review. Herba Polonica 60(2):56-66.

Qun-Lin Zhang, Bingmei M Fu, Zhang-Jin Zhang (2017). Borneol, a novel agent that improves central nervous system drug delivery by enhancing blood-brain barrier permeability. Drug Delivery 24(1):1037-1044.

Raina AP, Negi KS (2012). Chemical characterization of the essential oils of some aromatic plants of industrial interest from Uttarakhand, India, Medicinal Plants 4(2):1-6.

Rivas da Silva AC, Monteiro Lopes P, Barros de Azevedo MM, Machado Costa DC, Sales Alviano C, Sales Alviano D (2012). Biological activities of α-pinene and β-pinene enantiomers. Molecules 17(6):6305-6316.

Santos FA, Rao V (2000). Antiinflammatory and antinociceptive effects of 1,8-cineole a terpenoid oxide present in many plant essential oils. Phytotherapy Research 14(4):240-244.

Santos SE, Ribeiro FPRA, Menezes PMN, Duarte-Filho LAM, Quintans JSS, Quintas-Junior LJ, … Ribeiro LAA (2018). New insights on relaxant effects of (-)-borneol monoterpene in rat aortic rings. Fundamental and Clinical Pharmacology 33(2):148-158.

Savelev S, Okello E, Perry NSL, Wilkins RM, Perry EK (2003). Synergistic and antagonistic interactions of anticholinesterase terpenoids in Salvia lavandulaefolia essential oil. Pharmacology Biochemistry and Behavior 75(3):661-668.

Shahabi S, Jorsaraei SGHA, Moghadamnia AA, Barghi E, Zabihi E, Golsorkhtabar Amiri M, … Shamsai H (2014) The effect of camphor on sex hormones levels in rats. Cell Journal 16(2):231-234.

Smigielski K, Raj A, Krosowiak K, Gruska R (2009). Chemical composition of the essential oil of Lavandula angustifolia cultivated in Poland. Journal of Essential Oil-Bearing Plants 12(3):338-347.

Soković M, Glamočlija J, Marin PD, Brkić D, van Griensven LJLD (2010). Antibacterial effects of the essential oils of commonly consumed medicinal herbs using an in vitro model. Molecules 15(11):7532-7546.

Stranev S, Zagorcheva T, Atanassov I (2016). Lavender cultivation in Bulgaria - 21st century developments, breeding challenges and opportunities. Bulgarian Journal of Agricultural Science 22(4):584-590.

Tabari MA, Youssefi MR, Maggi F, Benelli G (2017). Toxic and repellent activity of selected monoterpenoids (thymol, carvacrol and linalool) against the castor bean tick, Ixodes ricinus (Acari: Ixodidae). Veterinary Parasitology 245:86-91.

Tekeli IO, Ateșșahin A, Sakin F, Aslan A, Çeribaşı M Yipel (2018). Protective effects of conventional and colon-targeted lycopene and linalool on ulcerative colitis induced by acetic acid in rats. Inflammopharmacology 2018:1-10.

Tomescu A, Rus C, Pop G, Alexa E, Șumălan R, Copolovici D, Negrea M (2015). Chemical composition of Lavandula angustifolia L. and Rosmarinus officinalis L. essential oils cultivated in West Romania. Research Journal of Agricultural Science 47(3):246-251.

Toncer O, Karaman S, Diraz E, Sogut T, Kizil S (2017). Essential oil composition of Thymus × citriodorus (Pers.) Schreb. at different harvest stages. Notulae Botanicae Horti Agrobotanici Cluj-Napoca 45(1):185-189.

Trombetta D, Castelli F, Sarpietro MG, Venuti V, Cristani M, Daniele C, … Bisignano G (2005). Mechanisms of antibacterial action of three monoterpenes. Antimicrobial Agents and Chemotherapy 49(6):2474-2478.

Umezu T, Sakata A, Ito H (2001). Ambulation-promoting effect of peppermint oil and identification of its active constituents. Pharmacology Biochemistry and Behavior 69(3-4):383-390.

Wang LP, Feng JF, Hu KL (2014). Progress in regulation effect of aromatic refreshing traditional Chinese medicine on BBB permeability and its mechanism (in Chinese). China Journal of Chinese Materia Medica 39(6):949-954.

Woelk, H, Schläfke S (2010). A multi-center, double-blind, randomised study of the Lavender oil preparation silexan in comparison to lorazepam for generalized anxiety disorder. Phytomedicine 17(2):94-99.

Woronuk G, Demissie Z, Rheault M, Mahmoud S (2011). Biosynthesis and therapeutic properties of Lavandula essential oil constituents. Planta Medica 77(1):7-15.

Zuccarini P (2009). Camphor risks and benefits of a widely used natural product. Journal of Applied Sciences and Environmental Management 13(2):69-74.

Downloads

Published

2019-06-11

How to Cite

OROIAN, C., ODAGIU, A., RACZ, C. P., OROIAN, I., MUREȘAN, I. C., DUDA, M., ILEA, M., BRAȘOVEAN, I., IEDERAN, C., & MARCHIȘ, Z. (2019). Composition of Lavandula angustifolia L. cultivated in Transylvania, Romania. Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 47(3), 643–650. https://doi.org/10.15835/nbha47311565

Issue

Vol. 47 No. 3 (2019)

Section

Research Articles
CITATION
DOI: 10.15835/nbha47311565

License

Copyright (c) 2019 Camelia OROIAN, Antonia ODAGIU, Csaba Pal RACZ, Ioan OROIAN, Iulia C. MUREȘAN, Marcel DUDA, Marioara ILEA, Ioan BRAȘOVEAN, Cristian IEDERAN, Zamfir MARCHIȘ

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

License:

© Articles by the authors; licensee UASVM and SHST, Cluj-Napoca, Romania. Papers published in the journal Notulae Botanicae Horti Agrobotanici Cluj-Napoca are open access distributed under the terms and conditions of the Creative Commons Attribution License (http://creativecommons.org/licenses).

Open Access Journal:

The journal allows the author(s) to retain publishing rights without restriction. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author.

Most read articles by the same author(s)